Posted on 09/24/2008

September 24, 2008--An analysis of emergency medical services-treated cardiac arrest outcomes in 10 areas in North America finds a five-fold difference in survival rates, according to a study in the Sept. 24 issue of the Journal of the American Medical Association.

In an accompanying editorial, Dr. Arthur B. Sanders and Dr. Karl B. Kern of The University of Arizona Sarver Heart Center write that "this wide variability in outcome emphasizes the pressing need for each community to first ‘know its numbers,' then concentrate on improving survival rates by focusing on locally identified problem areas within the chain of survival.

Sanders and Kern point to the example of two Wisconsin counties, where neurologically intact survival for patients with witnessed cardiac arrest and a shockable heart rhythm improved from 15 to 39 percent after emergency medical services implemented a modified resuscitation protocol developed by the UA Resuscitation Research Group. "Protocol and technique can be more important than location for survival of out-of-hospital cardiac arrest," the authors write in their editorial.

The UA Sarver Heart Center has played a crucial role in improving the ‘chain of survival' for out-of-hospital cardiac arrest through its concept of Cardiocerebral Resuscitation:

    * A simpler, more effective CPR for bystanders (compression-only CPR);
    * A modified resuscitation protocol for paramedics/firefighters;
    * Aggressive post-resuscitation hospital care, including catheterization to open blocked coronary vessels and therapeutic hypothermia (cooling) to prevent or minimize brain damage.

Approximately 166,000 to 310,000 Americans per year experience an out-of-hospital cardiac arrest, although resuscitation is not attempted in many of these cases. Dr. Graham Nichol, of the University of Washington, Seattle, and colleagues conducted a study to determine whether cardiac arrest incidence and outcome differed across geographic regions.

The study included data on all out-of-hospital cardiac arrests in 10 North American sites (eight American and two Canadian) from May 2006 to April 30, 2007, followed up to hospital discharge, and including data available as of June 28, 2008. Cases were assessed by organized emergency medical services personnel. The 10 sites were participants in the Resuscitation Outcomes Consortium, and were located in: Alabama, Dallas, Iowa, Milwaukee, Ottawa, Pittsburgh, Portland, Seattle, Toronto and Vancouver.

Among the 10 sites, with a total population of 21.4 million for the areas studied, there were 20,520 cardiac arrests assessed by emergency medical services personnel.