University of Colorado

Funding: This study was funded by the National Center for Advancing Translational Sciences/Colorado Clinical and Translational Science Awards Grant Number TL1 TR002533

Study details: This is a mixed-methods survey study completed by survivor and caregiver members of the SCAF. 

-We sought to understand how patient-provider relationship factors (i.e., patient-provider communication, patient readiness for discharge, and illness perceptions) impact quality of life in survivors and caregivers. 

-We also sought to understand how individual psychological factors (i.e., posttraumatic stress, anxiety, depression symptoms) impact quality of life in survivors and caregivers. 

-169 survivors completed the survey, with an average of 5 years post-event. 

-53 caregivers completed the survey, with an average of 3.5 years since their loved one’s event.

-15 survivors participated in interviews about their post-arrest experience. 

 

Peer-Reviewed Publications

  • Presciutti, A., Newman, M.M., Sawyer, K., Agarwal, S., & Perman, S.M. (2021). Gaps in provision of cognitive and psychological resources in cardiac arrest survivors with good neurologic recovery. Therapeutic Hypothermia and Temperature Management. Published online ahead of print. doi:10.1089/ther.2021.0003.
  • This study found that there are significant gaps in provision of cognitive and psychological resources in cardiac arrest survivors. 
  • A total of 73.1% (n = 122) survivors reported experiencing cognitive symptoms and 67.1% (n = 112) psychological symptoms since their cardiac arrest. When compared to these two proportions, provision of resources was significantly lower in all three metrics: (1) fewer discussions with providers about potential for developing cognitive symptoms (31%) and psychological symptoms (26.3%), (2) fewer neurologist appointments scheduled (8.4%) and psychologist appointments scheduled (4.8%), and (3) fewer referrals to mental health (6%).
  • Presciutti, A., Newman, M.M., Grigsby, J., Vranceanu, A.M., Shaffer, J.A., & Perman, S.M. (2021). Associations between posttraumatic stress symptoms and quality of life in cardiac arrest survivors and informal caregivers: A pilot survey study. Resuscitation Plus5, 100085. doi: 10.1016/j.resplu.2021.100085.
  • In this study, greater posttraumatic stress symptoms (PTS) were associated with worse quality of life in both cardiac arrest survivors and informal caregivers.
  • 1 in 4 cardiac arrest survivors showed significant PTS
  • 1 in 3 informal caregivers showed significant PTS
  • Presciutti, A., Newman, M.M., Vranceanu, A.M., Shaffer, J.A., & Perman, S.M. (2020). Associations between depression and anxiety with quality of life in cardiac arrest survivors with good         neurologic recovery and informal caregivers of cardiac arrest survivors. Journal of Affective Disorders Reports, 2, 100046.doi:10.1016/j.jadr.2020.100046.
  • In this study, depression and anxiety, not functional impairments or memory problems, were the strongest predictors of quality of life.
  • About 1 in 5 cardiac arrest survivors and informal caregivers showed significant depression
  • Nearly 1 in 3 cardiac arrest survivors and over 1 in 3 caregivers showed significant anxiety
  • Presciutti, A., Shaffer, J.A., Newman, M.M., & Perman, S.M. (2020). Modifiable provider-patient relationship factors and illness perceptions are associated with quality of life in survivors of cardiac arrest with good neurologic recovery. Resuscitation Plus, 3, 100008. doi: 10.1016/j.resplu.2020.100008.
  • Survivors that have threatening illness perceptions are more likely to have worse quality of life. 
  • Survivors that report poor provider-patient communication are more likely to have worse quality of life.
  • Survivors that report not having been ready for hospital discharge are more likely to have worse quality of life.

Poster Presentations

  1. Presciutti, A., Greenberg, J., Lester, E., Newman, M.M., Elmer, J., Shaffer, J.A., Vranceanu, A.M., & Perman, S.M. (2021, November). Mindfulness is inversely associated with psychological symptoms in long-term cardiac arrest survivors. Poster to be presented at the American Heart Association Resuscitation Science Symposium, Boston, MA.
    • In this study, we found that cardiac arrest survivors who practice more mindfulness have fewer psychological symptoms. 
  2. Presciutti, A., Anbarasan, D., Sumner, J.A., Grigsby, J., Vranceanu, A.M., Newman, M.M., Perman, S.M., & Shaffer J.A. (2021, April). Cardiac arrest survivors experience posttraumatic stress symptoms differently from informal caregivers of cardiac arrest survivors. Poster presented at the annual meeting and scientific sessions of the Society of Behavioral Medicine (virtual meeting).
    • In this study, we found that cardiac arrest survivors experience PTS differently than informal caregivers.
    • Survivors experience more negative alterations in emotions and thoughts compared to informal caregivers.
    • Informal caregivers experience more re-experiencing and avoidance symptoms compared to survivors.
  3. Presciutti, A., Perman, S.M., Newman, M.M., & Shaffer, J.A. (2020, November). Illness perceptions and readiness for discharge are associated with psychological symptoms in cardiac arrest survivors with good neurologic recovery. Poster presented at the American Heart Association Resuscitation Science Symposium (virtual meeting).
    • In this study, cardiac arrest survivors with more threatening illness perceptions and who reported lower readiness for discharge were more likely to have greater psychological symptoms.
  4. Presciutti, A., Newman, M.M., Vranceanu, A.M., Shaffer, J.A., & Perman, S.M. (2020, November). Posttraumatic stress symptoms are associated with quality of life in both cardiac arrest survivors with good neurologic recovery and caregivers. Poster presented at the American Heart Association Resuscitation Science Symposium (virtual meeting). ​​​​​​​
  5. Presciutti, A., Vranceanu, A.M., Newman, M.M., Shaffer, J.A., & Perman, S.M. (2020, November). Associations between specific PTSD symptoms and QoL in cardiac arrest survivors and informal caregivers. Poster presented at the Osher Center for Integrative Medicine at Harvard Medical School Network Forum, (virtual meeting).
    • In cardiac arrest survivors, negative alterations in emotions and thoughts and hyperarousal symptoms were the PTS symptom clusters most strongly associated with lower quality of life. 
    • In informal caregivers, negative alterations in emotions and thoughts was the PTS symptom cluster most strongly associated with lower quality of life.
  6. Presciutti, A., Shaffer, J.A., Newman, M.M., & Perman, S.M. (2020, April). Poor provider-patient communication, lack of readiness for discharge, and perceived illness threat are associated with quality of life after survival from cardiac arrest. Poster accepted for presentation at the annual meeting of the Association for Clinical and Translational Science, (meeting canceled).